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Weight-Loss Drug Xenical Approved In U.S. For Treatment Of Obesity
Weight-Loss Drug Xenical Approved In U.S. For Treatment Of Obesity
by Doctors Guide
When compared to diet alone, weight loss with Xenical has resulted in measurable improvements in certain obesity-related conditions, such as high blood pressure, high cholesterol and diabetes.
Unlike other anti-obesity agents that work in the brain to suppress appetite, Xenical through its fat-blocking mode of action works non-systemically in the gastrointestinal tract, not requiring entry into the bloodstream or brain. Xenical [pronounced: zen-i-cal] will be available to patients by prescription in the coming weeks.
Xenical is recommended for use three times daily with meals that contain up to 30 percent fat, consistent with current U.S. dietary guidelines. Blocking 1/3 of fat from digestion means that a patient who ingests 60 grams of fat a day may absorb only 40 grams of fat. The other 20 grams will be excreted through the digestive tract.
Xenical is indicated for obese patients with an initial body mass index (BMI) of greater than or equal to 30 or greater than or equal to 27 in the presence of other risk factors, such as high blood pressure, high cholesterol and diabetes. Body mass index (BMI) is the most widely accepted measurement of obesity.
Xenical is contraindicated in patients with chronic malabsorption syndrome or cholestasis. Organic causes of obesity, such as hypothyroidism, should be excluded before prescribing Xenical.
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